A digital fingerprint to help us understand how proteins change

05/12/2025

We are proud to share that our group has contributed to an important study on the impact of missense mutations, published in the Journal of Chemical Information and Modeling. The work, carried out with the contribution of our PhD student Clarissa Poles in collaboration with Scuola Superiore Meridionale in Naples, introduces ProSECFPs, a fast and lightweight computational approach that generates a digital fingerprint of proteins, enabling rapid and reliable interpretation of sequence variations. This advancement represents a significant step forward in applying artificial intelligence to protein analysis and precision medicine.

Read more on the Unipi News

AI and Chemistry: New Drug Design Research Published

13/05/2025
We are proud to share that our group contributed to a groundbreaking study, published in the European Journal of Medicinal Chemistry , on the use of artificial intelligence to design new bioactive molecules.

The research, developed in collaboration with the University of Bonn, with the contribution of our PhD student Lisa Piazza, introduces chemical language models capable of generating novel molecular structures from fragments, marking a major step forward in AI-driven drug discovery.

Read more on the Unipi News.